The Panthers are 1-7 all-time against the Steelers. Carolina is 1-3 at home and 0-4 on the road at Pittsburgh.
| Date | H/A | Result | Score (notes) |
|---|---|---|---|
| 12/22/96 | PITTSBURGH | W | 18-14 |
| 12/26/99 | at Pittsburgh | L | 20-30 |
| 12/15/02 | at Pittsburgh | L | 14-30 |
| 12/17/06 | PITTSBURGH | L | 3-37 |
| 12/23/10 | at Pittsburgh | L | 3-27 |
| 9/21/14 | PITTSBURGH | L | 19-37 |
| 11/8/18 | at Pittsburgh | L | 21-52 (TNF) |
| 12/18/22 | PITTSBURGH | L | 16-24 |