The Panthers are 3-3 all-time against the Titans. Carolina is 1-2 at home and 2-1 on the road at Tennessee.
| Date | H/A | Result | Score (notes) |
|---|---|---|---|
| 11/24/96 | at Houston | W | 31-6 |
| 10/19/03 | TENNESSEE | L | 17-37 |
| 11/4/07 | at Tennessee | L | 7-20 |
| 11/13/11 | TENNESSEE | L | 3-30 |
| 11/15/15 | at Tennessee | W | 27-10 |
| 11/3/19 | TENNESSEE | W | 30-20 |