The Saints are heavily favored by our weekly Pickin' It panelists to take care of Carolina on Monday Night Football, but a couple of analysts believe the Panthers will pull off a potential season-saving surprise at home.
Thirty-eight of the 40 prognosticators represented in the panel are siding with the Saints. The holdouts - hopeful holdouts from the Panthers' perspective - are Andrew Brandt for SI.com and Will Brinson for CBS Sports. Be sure to send them a Christmas card if their picks come through.
The Panthers lead the all-time series against the Saints, 24-23. Carolina has played New Orleans more than any other team in its history.