CHARLOTTE — The Panthers start the regular season with a home-heavy schedule, but they'll spend most of their time on the road during the preseason.
Dates and times of their preseason contests have been set, and they'll make their lone preseason appearance at Bank of America Stadium on Aug. 26 at 7 p.m. against the Bills, in the third preseason game.
With the preseason shortened to three games last year, that will be their lone home tune-up before starting the regular season with four of their first five games here.
The Panthers will open the preseason at Washington on Saturday, Aug. 13 p.m., in a 1 p.m. start.
They'll then play the Patriots on Aug. 19 at 7 p.m. Prior to that game, they will have a couple of days of joint practices with New England, getting some off-site work.
Last summer, they had joint practices with the Colts and Ravens.
TV and streaming information for preseason games will be announced at a later date. Click here to purchase preseason tickets.
Carolina is 2-5 all-time against Buffalo dating back to 1995.
Julius Peppers during the Panthers game against the Bills on Sunday, Sep. 16, 2017.
Carolina Panthers' Steve Smith (89) eludes a tackle by Buffalo Bills' Troy Vincent (23) during the first half of the the game at Ralph Wilson Stadium in Orchard Park, N.Y., Sunday, Nov. 27, 2005. (AP Photo/David Duprey)
Buffalo Bills' Willis McGahee (21) is tackled by Carolina Panthers' Chris Draft (52) during the second half of the game at Ralph Wilson Stadium in Orchard Park, N.Y., Sunday, Nov. 27, 2005. The Panthers won, 13-9. (AP Photo/David Duprey)
Carolina Panthers' Chris Gamble (20) celebrates his interception with teammate Ricky Manning Jr. (24) during the fourth quarter of the game against the Buffalo Bills at Ralph Wilson Stadium in Orchard Park, N.Y., Sunday, Nov. 27, 2005. The interception sealed the Panthers' 13-9 win over the Bills. (AP Photo/David Duprey)
Carolina Panthers' Michael Gaines (84) celebrates his touchdown reception in the end zone during the second half of the game against the Buffalo Bills at Ralph Wilson Stadium in Orchard Park, N.Y., Sunday, Nov. 27, 2005. The Panthers won, 13-9.(AP Photo/Don Heupel)
Carolina Panthers' DeShaun Foster (26) runs under pressure from Buffalo Bills' Eric King (29) and Jabari Greer (33) during the second half of the game at Ralph Wilson Stadium in Orchard Park, N.Y., Sunday, Nov. 27, 2005.The Panthers won, 13-9.(AP Photo/Don Heupel)
Buffalo Bills quarterback J. P. Losman is sacked by Carolina Panthers' Jordan Carstens (67) during the first half of the game at Ralph Wilson Stadium in Orchard Park, N.Y., Sunday, Nov. 27, 2005. (AP Photo/David Duprey)
during the Panthers game against the Bills on Sunday, Sep. 16, 2017.
Buffalo Bills running back Willis McGahee (21) is tackled by Carolina Panthers' Ricky Manning Jr. (24) and Chris Draft (52) in Orchard Park, N.Y., Sunday, Nov. 27, 2005. A year after producing 36 offensive touchdowns, the Bills have managed a mere 14 this season. Buffalo's offense ranks 30th overall. (AP Photo/David Duprey)
Cam Newton during the Panthers game against the Bills on Sunday, Sep. 16, 2017.
Kelvin Benjamin catches a pass during the Panthers game against the Bills on Sunday, Sep. 16, 2017.
Mario Addison during the Panthers game against the Bills on Sunday, Sep. 16, 2017.
Jonathan Stewart carries the football during the Panthers game against the Bills on Sunday, Sep. 16, 2017.
Carolina Panthers' Jake Delhomme (17) is shown against the Buffalo Bills in the first half of an NFL football game in Charlotte, N.C., Sunday, Oct. 25, 2009. (AP Photo/Nell Redmond)
Carolina Panthers' Jake Delhomme (17) scrambles against the Buffalo Bills in the first half of an NFL football game in Charlotte, N.C., Sunday, Oct. 25, 2009. (AP Photo/Chuck Burton)
Buffalo Bills' Ryan Fitzpatrick (14) scrambles against the Carolina Panthers in the second half of an NFL football game in Charlotte, N.C., Sunday, Oct. 25, 2009. (AP Photo/Chuck Burton)
Carolina Panthers' DeAngelo Williams (34) runs as Buffalo Bills' George Wilson (37) and Drayton Florence (29) defend in the first half of an NFL football game in Charlotte, N.C., Sunday, Oct. 25, 2009. (AP Photo/Chuck Burton)
Carolina Panthers' Steve Smith (89) is shown against the Buffalo Bills in the second half of Buffalo's 20-9 win in an NFL football game in Charlotte, N.C., Sunday, Oct. 25, 2009. (AP Photo/Rick Havner)
Buffalo Bills' Jairus Byrd (31) returns an interception against the Carolina Panthers in the second half of an NFL football game in Charlotte, N.C., Sunday, Oct. 25, 2009. (AP Photo/Rick Havner)
Carolina Panthers' Julius Peppers (90) is shown against the Buffalo Bills in the first half of an NFL football game in Charlotte, N.C., Sunday, Oct. 25, 2009. (AP Photo/Nell Redmond)
Buffalo Bills quarterback Doug Flutie (7) looks downfield as Carolina Panthers' Tim Morabito (90) closes in during the third quarter at Ericsson Stadium in Charlotte, N.C., Sunday, Oct. 25, 1998. (AP Photo/Alan Marler)
Buffalo Bills' Travis Henry (20) scores the game-winning touchdown over the Carolina Panthers during the fourth quarter of the game at Ralph Wilson Stadium in Orchard Park, N.Y., Sunday, Dec. 9, 2001. (AP Photo/David Duprey)
Carolina Panthers Star Lotulelei (98) grabs Buffalo Bills C.J. Spiller (28) while fending off a block from Colin Brown (74) during a 24-23 loss to the Buffalo Bills in an NFL football game, Sunday, Sept. 15, 2013, in Orchard Park, N.Y. (AP Photo/Bill Wippert)
Buffalo Bills cornerback Nickell Robey (37) pressures Carolina Panthers quarterback Cam Newton (1) during the first half of an NFL football game Sunday, Sept. 15, 2013, in Orchard Park, N.Y. (AP Photo/Gary Wiepert)
Buffalo Bills' C J Spiller (28) jumps over Carolina Panthers' Mike Mitchell (21) as Panthers' Thomas Davis (58) closes during an NFL football game Sunday, Sept. 15, 2013, in Orchard Park, N.Y. (AP Photo/Gary Wiepert)
Carolina Panthers receiver Ted Ginn Jr. celebrates a second half touchdown catch against the Buffalo Bills during an NFL football game Sunday, Sept. 15, 2013, in Orchard Park, N.Y. (AP Photo/Bill Wippert)
Buffalo Bills quarterback EJ Manuel passes against the Carolina Panthers in the third quarter of an NFL football game Sunday, Sept. 15, 2013, in Orchard Park, N.Y. (AP Photo/Bill Wippert)
Carolina Panthers tight end Greg Olsen (88) runs against Buffalo Bills outside linebacker Arthur Moats (52) after a pass reception in the first quarter of a NFL football game Sunday, Sept. 15, 2013, in Orchard Park, N.Y. (AP Photo/Gary Wiepert)
Carolina Panthers quarterback Cam Newton (1) begins a play against the Buffalo Bills in an NFL football game Sunday, Sept. 15, 2013, in Orchard Park, N.Y. (AP Photo/Bill Wippert)
Curtis Samuel has a pass broken up by the defense during the Panthers game against the Bills on Sunday, Sep. 16, 2017.
Christian McCaffrey carries the football during the Panthers game against the Bills on Sunday, Sep. 16, 2017.
Julius Peppers during the Panthers game against the Bills on Sunday, Sep. 16, 2017.
Luke Kuechly makes a tackle during the Panthers game against the Bills on Sunday, Sep. 16, 2017.
Cam Newton rushes during the Panthers game against the Bills on Sunday, Sep. 16, 2017.
