- Three different rookies started on defense in the opener, the most to start on defense in Week 1 in franchise history.
- Carolina outgained the Raiders, 388-372, in total yards and converted 7-of-13 third down opportunities.
- The Panthers punted just twice, their fewest since Week 13 of 2018. The team's only turnover came on downs late in the fourth quarter.
- Seven different players made receptions for Carolina, while nine different players had catches for Las Vegas.
- The Panthers had just one tackle for loss and did not record a sack for the first time since Week 2 of the 2018 season in Atlanta. The Raiders only recorded one sack.
- Christian McCaffrey rushed for 96 yards and two touchdowns. It marked his seventh career game with at least two rushing touchdowns, tied for third-most among all players since he entered the league in 2017.
- McCaffrey joined Chuck Foreman (37 rushing, 18 receiving) as the only players with 25-plus rushing touchdowns and 15-plus receiving scores in their first 50 career games.
- Robby Anderson caught a 75-yard touchdown reception from Teddy Bridgewater in the fourth quarter. It marked the longest touchdown reception for Carolina since 2016 when Ted Ginn went for 88 yards against the Raiders. It goes down as the 10th-longest touchdown reception in franchise history.
- Teddy Bridgewater threw for 270 yards and one touchdown with no interceptions in his Carolina debut, posting a passer rating of 98.9. His rating ranked fifth highest among passers in Week 1 in Panthers' history.
- Jeremy Chinn totaled eight tackles in his rookie debut. That ranks second among all Panthers rookies in Week 1 since 2000 when tackles were recorded, trailing only Lester Towns (10, 2000).
- Shaq Thompson totaled a team-high 12 tackles, just one shy of his single-game high of 13 (2018 vs. Baltimore).
- Pharoh Cooper averaged 14.5 yards on two punt returns and 27.3 yards on four kickoff returns.
- Running back Josh Jacobs ran for 93 yards and three touchdowns, a career high for the second-year player. It marked the third time since Week 8 of 2019 that Carolina has allowed a player to run for three touchdowns.
View game action photos from the Panthers-Raiders game in Week 1.