- Carolina totaled 414 net yards on offense, the fourth time the Panthers have topped 400 yards and first time since Week 9 at Green Bay.
- The Panthers converted 5-of-11 third-down opportunities for a 45 percent clip, marking the best third-down performance since Week 4 at Houston.
- Carolina lost the turnover battle, 3-1, as the Panthers are now a league-worst -14 in turnover differential since Week 8.
- Seattle totaled 154 yards on the ground, but the Panthers also tallied 145 rushing yards. It marked the fourth-most rushing yards in a game this season.
View photos from Week 15 as Carolina hosts Seattle.
- Christian McCaffrey rushed for 87 yards and two touchdowns, while also making eight catches for 88 yards. It marked McCaffrey's sixth game with at least 175 scrimmage yards this season, the most in the NFL.
- McCaffrey's total put him at 2,121 scrimmage yards for the season, passing Steve Smith's all-purpose record (1,994, 2001), and becoming the 15th player in NFL history to tally over 2,100 scrimmage yards in one of their first three seasons in the league.
- McCaffrey scored multiple TDs for the 12th time in his career, passing DeAngelo Williams (11) for the most career multi-TD games in franchise history.
- DJ Moore posted eight catches for 113 receiving yards, his fourth 100-yard receiving game this season. Moore now has 1,174 receiving yards, the seventh-best receiving season in franchise history.
- Curtis Samuel had 31 receiving yards and 23 rushing yards with nine total touches. Samuel now leads all NFL wide receivers with 126 rushing yards.
- Tre Boston tallied an interception in the second half for his third of the season. He is now tied with James Bradberry and Donte Jackson for the most picks on the team.
- Luke Kuechly tallied a game-high 17 tackles with two quarterback pressures. He now ranks third in the NFL with 131 tackles this season.
- Bruce Irvin recorded a sack and now has 6.5 sacks this season, second on the team.
- Joey Slye knocked in a 52-yard field goal, his seventh from 50+ this season. Slye now holds the franchise record for most 50-yard field goals in one season, passing Graham Gano (6, 2013).
- Chris Carson ran for 133 yards and two touchdowns. It marked Carson's sixth game with over 100 rushing yards this season as he ranks fourth in the league in rushing.