Cornerback records his first interception since the 2015 season, victimizing Joe Flacco.
Gerald McCoy finished with 5.0 sacks and seven tackles for loss in 2019 after Carolina signed him to a one-year contract.
"I couldn't be more thankful for these past nine years here. Just a great place to play. I'm proud of a lot of the things we accomplished, proud of how far we were able to take this team."
Jermaine Carter had a career-best 10 tackles in the season finale against the Saints.
Interim head coach Perry Fewell was emotional as he talked about the past four games as Carolina's interim head coach and what it meant to him as a local North Carolinian.
Watch the highlights from the New Orleans Saints' road win against the Carolina Panthers in Week 17 of the 2019 NFL regular season.
Watch every catch from Christian McCaffrey's milestone day in Week 17 as he became just the third player ever to eclipse the 1,000 yard mark in both rushing yards and receiving yards in a single season.
Christian McCaffrey scored his 19th total touchdown of the season, one shy of the franchise record.
Wide receiver Brandon Zylstra hauled in a 40-yard catch to set up a Panthers touchdown run.
Christian McCaffrey joined Roger Craig and Marshall Faulk as the only players in NFL history with at least 1,000 rushing yards and 1,000 receiving yards in the same season.
McCaffrey finished the first half just 22 yards of reaching 1,000 receiving yards on the season.
"When things go wrong, it's really easy to start pointing fingers," Christian McCaffrey said. "At the end of the day, we have to control what we can control."
Will Grier finished with 224 yards on 27-of-44 passing with no touchdowns and three interceptions.
Jermaine Carter started in place of the injured Shaq Thompson and tallied two tackles and a quarterback hurry.
"Our product doesn't look like that over the course of the week," Fewell said. "I have to find a way to make sure that product looks better on game day."
Watch the highlights from the Week 16 matchup between the Carolina Panthers and the Indianapolis Colts.
Carolina went for it on a fake punt and punter Michael Palardy hit DeAndrew White with a pass for the first down.
Carolina Panthers kicker Joey Slye drills a 50-yard field goal.
The Carolina Panthers' defense closes the door on Indianapolis Colts running back Marlon Mack for a turnover on downs inside the red zone.
Carolina Panthers rookie quarterback Will Grier throws on the run to Panthers wide receiver Jarius Wright for 19 yards.
Carolina Panthers quarterback Will Grier finds Panthers tight end Greg Olsen up the seam for a 28-yard gain.
Ross Cockrell tallied five tackles, including one for loss, in Sunday's home defeat to Seattle.
Luke Kuechly, Christian McCaffrey, Curtis Samuel, Trai Turner and Tre Boston evaluate Carolina's home loss to Seattle.
Watch the highlights from a Week 15 matchup between the Carolina Panthers and Seattle Seahawks.
Carolina Panthers running back Christian McCaffrey rushes for a 15-yard touchdown.
Carolina Panthers safety Tre Boston intercepts the pass by Seattle Seahawks wide receiver Josh Gordon.